The Julian laboratory is housed within Chemical Sciences at the University of California, Riverside. We have diverse research interests including: protein structure/folding, post translational modifications, radical chemistry, and aging.
The development of novel technologies continues to be a significant driver of science. For example, the invention of electrospray ionization enabled analysis of peptides and proteins by mass spectrometry, spurring tremendous advances and growth in the field of proteomics and many others. The Julian group develops mass spectrometry based tools to analyze molecular chemistry and structure, with targets ranging from protein quaternary structure to subtle differences in peptide epimers or even small molecule lipid isomers. Although there are many excellent methods for examining structure, mass spectrometry is usually faster, more sensitive, and amenable to high-throughput experiments, enabling analysis of complicated biological samples.