Bardeen Research Group

Department of Chemistry | University of California @ Riverside | 501 Big Springs Road | 127-131 CS-1

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Kerry M. Hanson
Department of Chemistry
University of California at Riverside
Riverside, CA 92521
Tel: 951.827.3079
Fax: 951.827.4713
kerry.hanson@ucr.edu

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Presentations

 

 

 

 

 

 

 

 

Thesis

University of California, Santa Cruz
Chemistry, Honors, 1992
Undergraduate Research Advisor: David S. Kliger

University of California, San Diego
Ph.D., Chemistry, 1998
Thesis Advisor: John D. Simon

University of Illinois at Urbana-Champaign
Postdoctoral Fellow, 1998-2001
Postdoctoral Advisor: Robert M. Clegg

Professional Research Chemist, Department of Chemistry, University of California, Riverside, Jan. 2005-present

Visiting Research Assistant Professor, Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign, Sept. 2001-Dec. 2004

Galderma Research Inc., La Jolla, CA
Internship, 1998

Kerry M. Hanson Consulting
Consultant to Sunscreen Indsutry, 2001-present


Cancer Research Foundation of America (2001-2003)
Skin Cancer Foundation Photobiology Award (2001-2002)
University of Illinois Research Board Fellowship (2001)
Hans P. Schaefer Award, Society of Cosmetic Chemists  (1999)
Galderma Research Inc. Merit Award (1998)
NIH-NIGMS Congressional Budget Testimony (1998) [ref: Proc. Natl. Acad. Sci., 95, 10576 (1998)]
Mrs. Walter J. Podbielniak Achievement Rewards for College Scientists (ARCS) Chemistry Scholarship (1995-1997)
ARCS Scholarship (1992-1994)
Drexler Scholarship in Chemistry (1992)
Honors, University of California at Santa Cruz (1992)


Current:   UV filter photochemistry and photostability. 

Post-doctoral and VRAP: Development of two-photon fluorescence imaging protocols to study chemical events (reactive oxygen species, pH) in skin.  Sunscreen-sensitization of UV-induced ROS in skin.  The effects of antioxidants upon UV-induced ROS in skin.

Graduate: Spectroscopy of the epidermal ultraviolet chromophore urocanic acid.  Ultrafast spectroscopy, photoacoustic spectroscopy.


1. Discovered that commonly used sunscreens can generate highly destructive reactive oxygen species in epidermis.

2. Showed that antixodiants used in skin formulations reduce the number of ROS in nucleated epidermal layers.

3. Dissemination of two-photon fluorescence imaging and lifetime methods to international personal care companies leading to the development of sunscreen products and ingredients.


"Photophysical studies for rational sunscreen design," UC Discovery Grant, UC Riverside & Merck Consumer Care, April 1, 2011-March 31, 2012.


Reviewer for (in alphabetical order)
European Journal of Pharmaceutics and Biopharmaceutics
Food Toxicology
Free Radical Biology and Medicine

Photochemistry and Photobiology
Nature Nanotechnology

Outreach

  • Science Fear! Night National Chemistry Week, UCR, 2013
  • Science Olympiad, UCR, 2012
  • Chemistry "States of Matter" and "Electricity & Magnetism" demonstrations for Taft Elementary School, Riverside, CA 1st, 3rd, & 4th grades (2007-present)
  • "Frankenweenie and the Scientific Method" and "Reaction Time and the Scientific Method," Taft Elementary School, Riverside, CA, 1st& 4th grades, (2013-present)
  • Children's Sunprotection Curriculum-Taft Elementary 1st Grade (2009)
  • Children's Sunprotection Curriculum-Child Development Center- UCR (2008)




  1. Hanson, K. M.; Beasley, D. G.; Meyer, T. A.; Bardeen, C. J. "Antioxidants in sunscreensfor improved ROS photoprotection." Cosm. Toil., 126, 712-716 (2011). Cover Article
  2. Bonda, C.; Pavlovic, A.; Hanson, K. M.; Bardeen, C. J. "Singlet quenching proves faster is better for photostability." Cosm. Toil., 125, 40-48 (2010)
    Best paper award, Society of Cosmetic Chemists, 2010.
  3.  Hanson, K.M.; Bardeen C.J. Application of nonlinear optical microscopy for imaging skin. Photochem. Photobiol.  85, 33-44 (2009).
  4. Hanson, K.M.; Davis, S.K.; Bardeen, C.J. "Two-photon standing-wave fluorescence correlation spectroscopy." Opt. Lett. 32, 1-4 (2007)
  5. Hanson, K. M.; Gratton, E.; Bardeen, C. J.  "Sunscreen enhancement of UV-induced ROS in the skin."  Free Radical Biology Medicine, 41, 1205-1212 (2006).
  6. Hanson, K. M.; Clegg, R. M. "Two-photon fluorescence imaging and ROS detection with the epidermis." Methods in Molecular Biology (Totowa, NJ, US) (2004), 289 (Epidermal Cells), 413-421.
  7. Lee, Erica H.; Faulhaber, D.; Hanson, K. M. et al. "Dietary lutein reduces UVR-induced inflammation and immunosuppression." J. Invest. Dermatol. 122, 510-517 (2004).
  8. Behne, M. J.; Barry, N. J.; Hanson, K. M. et al. "Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function." J. Invest. Dermatol. 120, 998-1006 (2003).
  9. Hanson, K. M.; Clegg, R. M. "Bioconvertible vitamin antioxidants improve sunscreen photoprotection against UV-induced reactive oxygen species."
    J Cosmet Sci. 54 589-98 (2003).
  10. Behne, M. J.; Meyer, J. W.; Hanson, K. M. et al. "NHE1 regulates the stratum corneum permeability barrier homeostasis." J. Biol. Chem. 277, 47399-47406 (2002).
  11. Hanson, K. M. Behne, M. J.; Barry, N. P. et al. "Two-photon fluoresecence lifetime imaginge of the skin stratum corneum pH gradient." Biophys. J. 83, 1682-1690 (2002).
  12. Hanson, K.M.; Clegg, R.M. "Observation and quantification of UV-induced ROS in ex vivo human skin." Photochem. Photobiol.76, 57-63 (2002).
  13. Hanson, K. M.; Simon J. D. "Epidermal trans-UA and the UVA-induced photoaging of the skin." Proc. Nat. Acad. Sci. 95, 10576-10578 (1998).
  14. Hanson, K. M.; Simon, J. D. "The origin of the wavelength-dependent photoreactivity of trans-UA." Photochem. Photobiol. 67, 538-540 (1998).
  15. Hanson, K. M.; Simon, J. D. "Photochemistry of UA: evidence that UA should be used with caution in cosmetic formulations." J. Soc. Cosm. Chem. 48, 151-157 (1997).
  16. Hanson, K. M.; Simon, J. D. "The photochemical isomerization kinetics of UA and their effects upon the in vitro and in vivo photoisomerization action spectra." Photochem. Photobiol. 66, 829 (1997).
  17. Hanson, K. M.; Li, B.; Simon, J. D. "A spectroscopic study of the epidermal chromophore trans-UA." J. Am. Chem. Soc. 48, 151 (1997).
  18. Li, B.; Hanson, K. M.; Simon, J. D. "The primary processes of the electronic excited state of t-UA." J. Phys. Chem. 101, 969 (1997).
  19. Fu, X.; Schmitz, F. J.; Govindan, M; Abbvas, S. A.; Hanson, K.M. et al. "Enzyme inhibitors: new and known polybrominated phenols and diphenyl ethers from fluor indo-pacific sponges." J. Nat. Prod. 58, 1384 (1995).
  20. Wallace-Williams, S. E.; Moller, S. et al. "Excited state s-cis rotamers produces by extreme red edge excition of all-trans-1,4,-diphenylbutadienes." J. Phys. Chem. 97, 9587 (1993).
  21. Wallace-Williams, S.E. et al. "Solvent and temperature effects on the exvcited inglet state absorption of diphenylbutadiene." Photochem. Photobiol. 56, 953 (1992).



News Articles:

  1. Hanson, K.M. “Room for Debate: What We Don’t Know.” New York Times, July 5, 2010. Invited article contributor to the NY Times’ Room for Debate blogspot discussion of the FDA’s anticipated labeling rules for sunscreens.

Radio & Television 

  1. KPCC LA, AirTalk with Larry Mantle, July 19, 2010, contributing panelist: “Sunscreen: Is It Safe?”
  2. WCVB - Boston's Channel 5, June, 2007
  3. CBC, Nova Scotia, September 2006
  4. KVMR, Nevada, September 2006
  5. KABC, LA, August 2006 
  6. KVCR LA, August 2006

Press Releases/Popular Press:

  1. UCR Press Release:
    “Sunscreens Can Damage Skin, Researchers Find
    Filters in sunscreens that keep out ultraviolet radiation can generate compounds that attack skin cells, say UCR chemists”
    (August 29, 2006)—reported in popular newspapers and magazines (2006-2009).
  2. UIUC Press Release:
    “ Study Shows Antioxidants Play Vital Role in Protecting Skin” (September 1, 2001) –reported in popular newspapers and magazines (2001-2002).

 

  1. Invited Speaker, SkinCare Ingredients 2011, CosmeticsDesign Europe & USA, William Reed, NY, Virtual Webinar
  2. Invited Speaker, SUNCARE 2020: Challenges and Future Imperatives for Improving Suncare for  American Consumers, The Coppertone Solar Research Center, Yale Club, New York-declined, April,  2010
  3. Annual Meeting of the Society of Cosmetic Chemists, New York, presented by Craig Bonda-Hallstar,  December 2010
  4. Keynote Speaker, LFD Workshop in Advanced Fluorescence Imaging and Dynamics, University of   California, Irvine, October 2010
  5. Invited Speaker, Introductory Course in Fluorescence Techniques, Spectroscopy and Microscopy, University of California, Irvine, April 2009.
  6. Annual Meeting, American Academy of Dermatology, San Francisco, presented by Thomas A. Meyer,   Schering-Plough HealthCare, March 2009.



The spectroscopy of the epidermal ultraviolet chromphore urocanic acid.